Bethune is a small town in Kershaw County, South Carolina, United States. The population was 345 at the 2016 census. It is part of the Columbia, South Carolina Metropolitan Statistical Area.
Europeans first moved into the area in the early 1800s finding members of the Kadapaw tribe living in the area. Originally, the settlers named the town Lynchwood and, in 1828, they established a post office. After the railroads came to the area, the town was officially chartered in 1900 and the name changed to honor Daniel Murdock Bethune.
As of the census of 2000, there were 352 people, 165 households, and 104 families residing in the town. The population density was 309.4 people per square mile (119.2/km²). There were 193 housing units at an average density of 169.6 per square mile (65.4/km²). The racial makeup of the town was 89.77% White, 9.66% African American, 0.28% Pacific Islander, 0.28% from other races. Hispanic or Latino of any race were 2.84% of the population.
There were 165 households out of which 21.8% had children under the age of 18 living with them, 49.7% were married couples living together, 10.9% had a female householder with no husband present, and 36.4% were non-families. 34.5% of all households were made up of individuals and 21.8% had someone living alone who was 65 years of age or older. The average household size was 2.13 and the average family size was 2.72.
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